Prediction Model of Postoperative Major Complications after Hepatectomy for Hepatocellular Carcinoma (HCC) among Patients with Chronic Hepatitis B Infection

This easy-to-use prediction model aims to calculate the probability of postoperative 30-day major complications among patients with chronic hepatitis B (HBV) infection undergoing hepatectomy for hepatocellular carcinoma (HCC). This online tool can be useful in clinical practice by offering information based on patients’ preoperative clinical characteristics and planned surgery.

This prediction tool was based on the data of 2,762 patients with chronic HBV infection who underwent curative-intent hepatectomy for HCC from several tertiary hospitals in China, which incorporated 7 parameters: albumin-bilirubin (ALBI) score, aspartate transaminase to platelet index (APRI) score, diabetes mellitus, cirrhosis, tumor burden (within or beyond the Milan criteria), concurrent HCV infection, and preoperative HBV-DNA level. In this way, this prediction model could facilitate individualized surgical decision-making, and those patients at high risk of major complications should receive more intensive perioperative care and surveillance.